Feel Like Yourself Again — Vagizole™ (metronidazole vaginal gel), 0.75%, a prescription-strength treatment for bacterial vaginosis
Metronidazole Vaginal Gel
One application daily
Included with every package
Understanding Bacterial Vaginosis
Bacterial vaginosis (BV) occurs when the delicate balance of good and harmful bacteria in the vagina is disrupted. This imbalance can lead to uncomfortable symptoms.
A healthy vaginal environment is dominated by good bacteria that help protect you.
An overgrowth of harmful bacteria can disrupt pH and lead to BV symptoms.
Up to 1 in 3 women may experience bacterial vaginosis during their lifetime.
BV is common, treatable, and is not a sign of poor hygiene.
Source: Bacterial vaginosis, Nature Reviews Disease Primers, 2025.
Clinical data
The CDC's 2021 Sexually Transmitted Infections Treatment Guidelines list intravaginal metronidazole gel 0.75% as a first-line recommended regimen for bacterial vaginosis, alongside oral metronidazole and clindamycin cream.
CDC-recommended regimens for bacterial vaginosis
| Metronidazole gel 0.75% | One 5 g applicator intravaginally, once daily for 5 days — this is Vagizole™ |
| Metronidazole oral | 500 mg by mouth, twice daily for 7 days |
| Clindamycin cream 2% | One 5 g applicator intravaginally at bedtime for 7 days |
Source: CDC Sexually Transmitted Infections Treatment Guidelines, 2021. Your doctor will determine which regimen is right for you.
FDA status
Manufactured in the USA
Official NDC assigned to Vagizole™ 70 g carton with five applicators.
Available only with a healthcare provider's prescription.
Manufactured under current Good Manufacturing Practice.
The product
0.75% metronidazole for effective BV treatment.
Apply one applicator intravaginally once daily for 5 days.
Targets the cause of BV with proven efficacy.
Smooth gel formula for gentle application.
One applicator per day for 5 days. Stay consistent for best results.
Clinically proven relief from bacterial vaginosis symptoms.
What's in the box
Each carton includes a 70 gram tube and 5 pre-measured applicators — no guesswork, no separate purchases.
Prescription strength 0.75% metronidazole vaginal gel.
Pre-measured, disposable applicators for single use.
Easy-to-follow patient instructions included.
NDC 67867-002-70. FDA-listed, Rx only prescription product.
How it works
Puncture the tube's seal, screw on the applicator, and gently squeeze from the bottom — it stops filling automatically once full.
Insert the applicator comfortably, then press the plunger to release the gel.
Use once daily at bedtime, or twice daily, for 5 days as your doctor prescribes.
Safety information
A summary of key safety information, organized for easy reading. This does not replace the Full Prescribing Information — see the footer of this page and the accompanying product brochure for complete details.
Vagizole™ (metronidazole vaginal gel, 0.75%) is a prescription medicine indicated for the treatment of bacterial vaginosis in non-pregnant women.
Do not use Vagizole if you have a known hypersensitivity to metronidazole, parabens, or other nitroimidazole derivatives.
The most commonly reported effects include vaginal discharge, vaginal yeast infection, vulvar or vaginal irritation, and pelvic discomfort, along with gastrointestinal discomfort, nausea, and an unpleasant taste.
For intravaginal use only — not for ophthalmic, dermal, or oral use. Store at controlled room temperature, 15° to 30°C (59° to 86°F). Protect from freezing. Keep out of reach of children.
FAQs
Yes. Vagizole™ (metronidazole vaginal gel, 0.75%) is labeled under U.S. FDA regulations as a prescription treatment for bacterial vaginosis, identified by NDC 87687-002-70.
Metronidazole vaginal gel 0.75%, dosed once daily for 5 days, is one of the first-line regimens listed in the CDC's STI Treatment Guidelines for bacterial vaginosis — the same active ingredient, strength, and regimen as Vagizole.
Yes, Vagizole is available by prescription only. Talk to your doctor if you think you may have BV.
There's no experience to date with Vagizole in pregnant patients, and it should be used during pregnancy only if clearly needed. Metronidazole is secreted in breast milk, so talk to your doctor about nursing before starting treatment.
Talk to your doctor
Vagizole™ is available by prescription only. Your healthcare provider can confirm a diagnosis of bacterial vaginosis and decide if Vagizole is the right treatment for you.